The principle of action and composition of the drug
Nolvadex is a non-steroidal antagonist of estrogens. It specifically binds to estrogen receptors in peripheral and tumor tissues, thus, eliminating the effect of estrogens that are produced in the body and stimulate the growth of cancer cells.
Nolvadex from Canada slows the progression of the tumor process. After taking a single dose the ability to block estrogens will retain a few weeks. The drug causes ovulation in women and increases the level of LH and FSH in men with oligospermia.
Nolvadex is prescribed when:
- estrogen-dependent breast tumors in postmenopausal women;
- endometrial cancer.
How to take the Nolvadex properly?
For adults (including elderly people) the daily dose of the medication is from 20 to 40 mg and is taken either divided doses twice a day, or a single daily dose.
Does it require a medical prescription?
This drug is the rx drug and requires a medical prescription. Without it you will not be able to purchase this drug in any of local pharmacies. Even by taking into account the fact that you are able to order this medication online without prescription from your doctor, it is very important to get consultations from the specialist prior ordering this medication.
What are the contraindications for Nolvadex?
Among the most important contraindications for generic Nolvadex taking are:
- Hypersensitivity to the main component of the drug;
When signs of thrombosis of the veins of the lower extremities (pain in the legs or their swelling), thromboembolism of the branches of the pulmonary artery (dyspnea), the drug taking should be immediately stopped.
In patients with hyperlipidemia, the concentration of cholesterol and TG in serum should be monitored during treatment.
During treatment with Nolvadex, keep caution when driving vehicles and engaging in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.
Combinations with other drugs
When combined with cytostatics, the risk of thrombosis increases. Estrogen may reduce the therapeutic effect of tamoxifen (the main component of the generic Nolvadex). Can be used in combination with progestins. Potentiates the effect of indirect anticoagulants.
How to store the medication?
Both the generic Nolvadex and the original drug should be stored at a temperature of up to 30 ° C
What are the possible side effects of Nolvadex?
Nolvadex can cause the following undesirable reactions:
- gastrointestinal disorders and nausea;
- uterine bleeding, endometrial hyperplasia, uterine fibroid, pruritus vulva;
- fluid retention in the body;
- thrombocytopenia, leukopenia;
- pain in the bones;
- changes in the retina of the eye;
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