What’s Naltrexone (Revia)?
Naltrexone (Revia) – a drug for the treatment of chronic alcoholism and the prevention of relapse.
The mechanism of action is due to the blockade of aldehyde dehydrogenase involved in the metabolism of ethanol. The blockade of this enzyme leads to an increase in the concentration of the metabolite of ethanol – acetaldehyde, which causes negative sensations (including flushing to the face, nausea, tachycardia, dyspnea), which make it extremely unpleasant to drink alcohol after taking the drug and lead to a conditioned reflex aversion to taste and smell of alcoholic beverages.
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