Antibiotic of the tetracycline group. It has a bacteriostatic effect by suppressing protein synthesis by reversible binding to the ribosomal subunit of 30S sensitive microorganisms.
It is active against gram-positive bacteria: Staphyloccocus aureus, Streptococcus spp., Nocardia spp., Listeria spp., Bacillus anthracis; Gram-negative bacteria: Neisseria meningitidis, Bartonella bacilliformis, Vibrio cholerae, Esherichia coli, Klebsiella spp., Shigella spp., Acinetobacter spp., Haemophilus spp .; anaerobic bacteria: Clostridium spp., Bacteroides spp.
Minomycin is also active against Mycobacterium spp. (including Mycobacterium leprae), Chlamydia spp., Ureaplasma urealyticum, Treponema pallidum.
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