What’s Dutas (Dutasteride)?
Dutas (Dutasteride) – a drug for the treatment of benign prostatic hyperplasia. Dutasteride is a double inhibitor of 5α-reductase. Suppresses the activity of 5α-reductase isoenzymes 1 and 2 types, which are responsible for the conversion of testosterone into 5α-dihydrotestosterone (DHT). Dihydrotestosterone is the main androgen responsible for the hyperplasia of the glandular tissue of the prostate gland. The maximum effect of dutasteride on decreasing concentrations of DHT is dose-dependent and observed 1-2 weeks after the start of treatment. After 1 and 2 weeks of taking dutasteride at a dose of 500 μg / day, the average serum concentrations of dihydrotestosterone decrease by 85% and 90%.
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